Spanish researchers at the University of Navarra have conclusively linked increased ambient air temperatures with an increase in the neural damage done by consumed ecstasy.
Taking ecstasy in a hot club environment increases the risks of neural damage. Heat makes it worse. The ambient temperature at which ecstasy is taken influences the neural damage done by the drug. Using animal model studies in which rats were dosed with ecstasy at temperatures ranging from 15 to 30 degrees centigrade, and examining the resultant neural damage, researchers have causally linked the ambient air temperature during consumption with an increased risk for neural damage and deficits.
They explain that if ecstasy were somehow dosed directly into the brain, there would be no risk of neural damage, and the damage caused seems to be induced by the bodily metabolism of the consumed drug. Higher ambient air temperatures increase the speed and extent of the metabolism, and the higher the ambient air temperature, the greater the risk of neural damage. The problem for drug users is that people most often take ecstasy in a club setting, in which many people may share a poorly ventilated and confined space, greatly increasing ambient temperatures. A heated club environment exacerbates the neural damage done by increasing the metabolism of the consumed drug.
The seratonergic systems, those that regulate mood, memory and sleep, seem most affected and damaged by ecstasy; and researchers who have long known that heavy ecstasy consumption can induce serious neural deficits, now also realize that even occasional and minimal consumption does also induce some damage. If you take ecstasy, even once, you do likely suffer some degree of neural consequences, and the more you take it, the greater the permanent damage done.
It now seems that damage can be alternatively minimized or increased depending on the temperature in which the drug is taken. Hard dancing ecstasy consumers, already at risk for fatal hyperthermia through a loss in internal temperature regulating mechanisms, have another reason to fear the heat of the dance club. If you must take ecstasy…do it in the snow!